mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation

The mammalian target of rapamycin complex 1 (mTORC1) is activated by extracellular factors that control bone accrual. However, the direct role of this complex in osteoblast biology remains to be determined. To investigate this question, we disrupted mTORC1 function in preosteoblasts by targeted dele...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Fitter, Stephen, Matthews, Mary P., Martin, Sally K., Xie, Jianling, Ooi, Soo Siang, Walkley, Carl R., Codrington, John D., Ruegg, Markus A., Hall, Michael N., Proud, Christopher G., Gronthos, Stan, Zannettino, Andrew C. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359426/
https://ncbi.nlm.nih.gov/pubmed/28069737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00668-16
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