A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity

Top-down proteomics (TDP) allows precise determination/characterization of the different proteoforms derived from the expression of a single gene. In this study, we targeted apolipoprotein A-I (ApoA-I), a mediator of high-density-lipoprotein cholesterol efflux (HDL-E), which is inversely associated...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Proteome Res
Egile Nagusiak: dos Santos Seckler, Henrique, Fornelli, Luca, Mutharasan, R. Kannan, Thaxton, C. Shad, Fellers, Ryan, Daviglus, Martha, Sniderman, Allan, Rader, Daniel, Kelleher, Neil L., Lloyd-Jones, Donald M., Compton, Philip D., Wilkins, John T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162093/
https://ncbi.nlm.nih.gov/pubmed/29649363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00100
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