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Reducing protein oxidation in low-flow electrospray enables deeper investigation of proteoforms by top down proteomics

Enabling the implementation of top down proteomic techniques within clinical workflows requires a dramatic increase in sensitivity. It has been previously demonstrated that electrospray ionization (ESI) becomes more efficient with decreasing volumetric flow rates at the emitter. Therefore, narrow in...

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Podrobná bibliografie
Vydáno v:EuPA Open Proteom
Hlavní autoři: Kim, Kyunggon, Compton, Philip D., Toby, Timothy K., Thomas, Paul M., Wilkins, John T., Mutharasan, R. Kannan, Kelleher, Neil L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704458/
https://ncbi.nlm.nih.gov/pubmed/26753126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euprot.2015.05.005
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