Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress

Oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). The dry form of AMD (geographic atrophy) is characterized by loss of RPE, photoreceptors, and macular pigments. The cumulative effects of oxidative stress impact mitochondrial function in RPE. In Sod2(flox/...

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Vydáno v:PLoS One
Hlavní autoři: Biswal, Manas R., Justis, Bradley D., Han, Pingyang, Li, Hong, Gierhart, Dennis, Dorey, Cheryl K., Lewin, Alfred S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161850/
https://ncbi.nlm.nih.gov/pubmed/30265681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203816
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