Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress

Oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). The dry form of AMD (geographic atrophy) is characterized by loss of RPE, photoreceptors, and macular pigments. The cumulative effects of oxidative stress impact mitochondrial function in RPE. In Sod2(flox/...

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Udgivet i:PLoS One
Main Authors: Biswal, Manas R., Justis, Bradley D., Han, Pingyang, Li, Hong, Gierhart, Dennis, Dorey, Cheryl K., Lewin, Alfred S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161850/
https://ncbi.nlm.nih.gov/pubmed/30265681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203816
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