Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress

Oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). The dry form of AMD (geographic atrophy) is characterized by loss of RPE, photoreceptors, and macular pigments. The cumulative effects of oxidative stress impact mitochondrial function in RPE. In Sod2(flox/...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Biswal, Manas R., Justis, Bradley D., Han, Pingyang, Li, Hong, Gierhart, Dennis, Dorey, Cheryl K., Lewin, Alfred S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161850/
https://ncbi.nlm.nih.gov/pubmed/30265681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203816
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