Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2

Adenosine deaminases acting on RNA (ADARs) catalyze the deamination of adenosine (A) to inosine (I). A-to-I RNA editing targets double-stranded RNA (dsRNA), and increases the complexity of gene regulation by modulating base pairing-dependent processes such as splicing, translation, and microRNA (miR...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA Biol
Prif Awduron: Ishiguro, Soh, Galipon, Josephine, Ishii, Rintaro, Suzuki, Yutaka, Kondo, Shinji, Okada-Hatakeyama, Mariko, Tomita, Masaru, Ui-Tei, Kumiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2018
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161747/
https://ncbi.nlm.nih.gov/pubmed/29950133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1486658
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