Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2

Adenosine deaminases acting on RNA (ADARs) catalyze the deamination of adenosine (A) to inosine (I). A-to-I RNA editing targets double-stranded RNA (dsRNA), and increases the complexity of gene regulation by modulating base pairing-dependent processes such as splicing, translation, and microRNA (miR...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Ishiguro, Soh, Galipon, Josephine, Ishii, Rintaro, Suzuki, Yutaka, Kondo, Shinji, Okada-Hatakeyama, Mariko, Tomita, Masaru, Ui-Tei, Kumiko
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161747/
https://ncbi.nlm.nih.gov/pubmed/29950133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1486658
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