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Amorphous Nanosuspensions Aggregated from Paclitaxel–Hemoglobulin Complexes with Enhanced Cytotoxicity

Amorphous nanosuspensions (ANSs) enable rapid release and improved delivery of a poorly water-soluble drug; however, their preparation is challenging. Here, using hemoglobin (Hb) as a carrier, ANSs aggregated from paclitaxel (PTX)–Hb complexes were prepared to improve delivery of the hydrophobic ant...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Qin, Chao, Xin, Xiaofei, Pei, Xue, Yin, Lifang, He, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161098/
https://ncbi.nlm.nih.gov/pubmed/30011808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030092
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