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A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy

Clinically, paclitaxel (PTX) is one of most commonly prescribed therapies against a wide range of solid neoplasms. Despite its success, the clinical applicability of PTX (Taxol(®)) is severely hampered by systemic toxicities induced by Cremophor EL. While attempts to bypass the need for Cremophor EL...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Yin, Tingjie, Dong, Lihui, Cui, Bei, Wang, Lei, Yin, Lifang, Zhou, Jianping, Huo, Meirong
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686322/
https://ncbi.nlm.nih.gov/pubmed/26715846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S92697
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