Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling

Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes survival signaling responses in vitro; thus, we hypothesize that this pathway can miti...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Grisanti, Laurel A., Thomas, Toby P., Carter, Rhonda L., de Lucia, Claudio, Gao, Erhe, Koch, Walter J., Benovic, Jeffrey L., Tilley, Douglas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160776/
https://ncbi.nlm.nih.gov/pubmed/30279730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.26619
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