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Early adolescent nicotine exposure affects later-life hippocampal mu-opioid receptors activity and morphine reward but not physical dependence in male mice

RATIONALE. There is extensive literature regarding nicotine-opioid functional interactions. The possibility that use of nicotine products during adolescence might increase the risk of substance abuse such as morphine later in adulthood is particularly relevant to the current opioid crisis. OBJECTIVE...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Kota, Dena, Alajaji, Mai, Bagdas, Deniz, Selley, Dana E., Sim-Selley, Laura J., Damaj, M. Imad
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160313/
https://ncbi.nlm.nih.gov/pubmed/30125591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2018.08.006
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