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New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice
Varenicline, a partial agonist for α4β2* nicotinic acetylcholine receptors (nAChRs) and a full agonist for α3β4 and α7 nAChRs, is approved for smoking cessation treatment. Although, partial agonism at α4β2* nAChRs is believed to be the mechanism underlying the effects of varenicline on nicotine rewa...
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| Publicado no: | Neuropharmacology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054891/ https://ncbi.nlm.nih.gov/pubmed/29860196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.05.025 |
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