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New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice

Varenicline, a partial agonist for α4β2* nicotinic acetylcholine receptors (nAChRs) and a full agonist for α3β4 and α7 nAChRs, is approved for smoking cessation treatment. Although, partial agonism at α4β2* nAChRs is believed to be the mechanism underlying the effects of varenicline on nicotine rewa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropharmacology
Prif Awduron: Bagdas, Deniz, Alkhlaif, Yasmin, Jackson, Asti, Carroll, F. Ivy, Ditre, Joseph W., Damaj, M. Imad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054891/
https://ncbi.nlm.nih.gov/pubmed/29860196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.05.025
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