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New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice

Varenicline, a partial agonist for α4β2* nicotinic acetylcholine receptors (nAChRs) and a full agonist for α3β4 and α7 nAChRs, is approved for smoking cessation treatment. Although, partial agonism at α4β2* nAChRs is believed to be the mechanism underlying the effects of varenicline on nicotine rewa...

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Bibliografiska uppgifter
I publikationen:Neuropharmacology
Huvudupphovsmän: Bagdas, Deniz, Alkhlaif, Yasmin, Jackson, Asti, Carroll, F. Ivy, Ditre, Joseph W., Damaj, M. Imad
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054891/
https://ncbi.nlm.nih.gov/pubmed/29860196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.05.025
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