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Mu Opioid Receptor Binding Correlates with Nicotine Dependence and Reward in Smokers

The rewarding effects of nicotine are associated with activation of nicotine receptors. However, there is increasing evidence that the endogenous opioid system is involved in nicotine's rewarding effects. We employed PET imaging with [(11)C]carfentanil to test the hypotheses that acute cigarett...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kuwabara, Hiroto, Heishman, Stephen J., Brasic, James R., Contoreggi, Carlo, Cascella, Nicola, Mackowick, Kristen M., Taylor, Richard, Rousset, Olivier, Willis, William, Huestis, Marilyn A., Concheiro, Marta, Wand, Gary, Wong, Dean F., Volkow, Nora D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262264/
https://ncbi.nlm.nih.gov/pubmed/25493427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113694
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