Mu Opioid Receptor Binding Correlates with Nicotine Dependence and Reward in Smokers

The rewarding effects of nicotine are associated with activation of nicotine receptors. However, there is increasing evidence that the endogenous opioid system is involved in nicotine's rewarding effects. We employed PET imaging with [(11)C]carfentanil to test the hypotheses that acute cigarett...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kuwabara, Hiroto, Heishman, Stephen J., Brasic, James R., Contoreggi, Carlo, Cascella, Nicola, Mackowick, Kristen M., Taylor, Richard, Rousset, Olivier, Willis, William, Huestis, Marilyn A., Concheiro, Marta, Wand, Gary, Wong, Dean F., Volkow, Nora D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262264/
https://ncbi.nlm.nih.gov/pubmed/25493427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113694
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