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Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer
Tumor relapse is the leading cause of death in breast cancer, largely due to the fact that recurrent tumors are frequently resistant to chemotherapy. We previously reported that downregulation of the proapoptotic protein Par-4 promotes tumor recurrence in genetically engineered mouse models of breas...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6159989/ https://ncbi.nlm.nih.gov/pubmed/30148456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99481 |
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