טוען...
Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming
Prostate cancer is an androgen-dependent disease subject to interactions between the tumor epithelium and its microenvironment. Here, we found that epigenetic changes in prostatic cancer-associated fibroblasts (CAF) initiated a cascade of stromal-epithelial interactions. This facilitated lethal pros...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6159981/ https://ncbi.nlm.nih.gov/pubmed/30047926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99397 |
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