Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis

Hemorrhagic cystitis is an inflammatory and ulcerative bladder condition associated with systemic chemotherapeutics, like cyclophosphomide. Earlier, we reported reactive oxygen species resulting from cyclophosphamide metabolite, acrolein, causes global methylation followed by silencing of DNA damage...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haldar, Subhash, Dru, Christopher, Mishra, Rajeev, Tripathi, Manisha, Duong, Frank, Angara, Bryan, Fernandez, Ana, Arditi, Moshe, Bhowmick, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171776/
https://ncbi.nlm.nih.gov/pubmed/27995963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39257
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