Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis

Hemorrhagic cystitis is an inflammatory and ulcerative bladder condition associated with systemic chemotherapeutics, like cyclophosphomide. Earlier, we reported reactive oxygen species resulting from cyclophosphamide metabolite, acrolein, causes global methylation followed by silencing of DNA damage...

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Foilsithe in:Sci Rep
Main Authors: Haldar, Subhash, Dru, Christopher, Mishra, Rajeev, Tripathi, Manisha, Duong, Frank, Angara, Bryan, Fernandez, Ana, Arditi, Moshe, Bhowmick, Neil A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171776/
https://ncbi.nlm.nih.gov/pubmed/27995963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39257
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