Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis

Hemorrhagic cystitis is an inflammatory and ulcerative bladder condition associated with systemic chemotherapeutics, like cyclophosphomide. Earlier, we reported reactive oxygen species resulting from cyclophosphamide metabolite, acrolein, causes global methylation followed by silencing of DNA damage...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Haldar, Subhash, Dru, Christopher, Mishra, Rajeev, Tripathi, Manisha, Duong, Frank, Angara, Bryan, Fernandez, Ana, Arditi, Moshe, Bhowmick, Neil A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171776/
https://ncbi.nlm.nih.gov/pubmed/27995963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39257
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