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Epigenetic changes in fibroblasts drive cancer metabolism and differentiation
Genomic changes that drive cancer initiation and progression contribute to the co-evolution of the adjacent stroma. The nature of the stromal reprogramming involves differential DNA methylation patterns and levels that change in response to the tumor and systemic therapeutic intervention. Epigenetic...
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| Veröffentlicht in: | Endocr Relat Cancer |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Bioscientifica Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6859444/ https://ncbi.nlm.nih.gov/pubmed/31627186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-19-0347 |
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