Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferation

Fibroblast-like synoviocytes (FLSs) are critical to synovial aggression and joint destruction in rheumatoid arthritis (RA). The role of long noncoding RNAs (lncRNAs) in RA is largely unknown. Here, we identified a lncRNA, LERFS (lowly expressed in rheumatoid fibroblast-like synoviocytes), that negat...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Zou, Yaoyao, Xu, Siqi, Xiao, Youjun, Qiu, Qian, Shi, Maohua, Wang, Jingnan, Liang, Liuqin, Zhan, Zhongping, Yang, Xiuyan, Olsen, Nancy, Zheng, Song Guo, Xu, Hanshi
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159954/
https://ncbi.nlm.nih.gov/pubmed/30198906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97965
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