Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase Activation

OBJECTIVE: To investigate the role of glycogen metabolism in regulating rheumatoid fibroblast-like synoviocyte (FLS)-mediated synovial inflammation and its underlying mechanism. METHODS: FLSs were separated from synovial tissues (STs) obtained from rheumatoid arthritis (RA) patients. Glycogen conten...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shi, Maohua, Wang, Jingnan, Xiao, Youjun, Wang, Cuicui, Qiu, Qian, Lao, Minxi, Yu, Yangtao, Li, Zhifeng, Zhang, Hongwei, Ye, Yujin, Liang, Liuqin, Yang, Xiuyan, Chen, Guoqiang, Xu, Hanshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072843/
https://ncbi.nlm.nih.gov/pubmed/30100905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01714
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