The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ(42) and Alzheimer Amyloid Plaques

Alzheimer’s disease (AD) is the most common form of dementia and there is no successful treatment available. Evidence suggests that fibril formation of the amyloid β-peptide (Aβ) is a major underlying cause of AD, and treatment strategies that reduce the toxic effects of Aβ amyloid are sought for. T...

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Veröffentlicht in:J Alzheimers Dis Rep
Hauptverfasser: Dolfe, Lisa, Tambaro, Simone, Tigro, Helene, Del Campo, Marta, Hoozemans, Jeroen J.M., Wiehager, Birgitta, Graff, Caroline, Winblad, Bengt, Ankarcrona, Maria, Kaldmäe, Margit, Teunissen, Charlotte E., Rönnbäck, Annica, Johansson, Jan, Presto, Jenny
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159705/
https://ncbi.nlm.nih.gov/pubmed/30480246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-170051
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