The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ(42) and Alzheimer Amyloid Plaques

Alzheimer’s disease (AD) is the most common form of dementia and there is no successful treatment available. Evidence suggests that fibril formation of the amyloid β-peptide (Aβ) is a major underlying cause of AD, and treatment strategies that reduce the toxic effects of Aβ amyloid are sought for. T...

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Publicado en:J Alzheimers Dis Rep
Main Authors: Dolfe, Lisa, Tambaro, Simone, Tigro, Helene, Del Campo, Marta, Hoozemans, Jeroen J.M., Wiehager, Birgitta, Graff, Caroline, Winblad, Bengt, Ankarcrona, Maria, Kaldmäe, Margit, Teunissen, Charlotte E., Rönnbäck, Annica, Johansson, Jan, Presto, Jenny
Formato: Artigo
Idioma:Inglês
Publicado: IOS Press 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159705/
https://ncbi.nlm.nih.gov/pubmed/30480246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-170051
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