The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ(42) and Alzheimer Amyloid Plaques

Alzheimer’s disease (AD) is the most common form of dementia and there is no successful treatment available. Evidence suggests that fibril formation of the amyloid β-peptide (Aβ) is a major underlying cause of AD, and treatment strategies that reduce the toxic effects of Aβ amyloid are sought for. T...

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Pubblicato in:J Alzheimers Dis Rep
Autori principali: Dolfe, Lisa, Tambaro, Simone, Tigro, Helene, Del Campo, Marta, Hoozemans, Jeroen J.M., Wiehager, Birgitta, Graff, Caroline, Winblad, Bengt, Ankarcrona, Maria, Kaldmäe, Margit, Teunissen, Charlotte E., Rönnbäck, Annica, Johansson, Jan, Presto, Jenny
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159705/
https://ncbi.nlm.nih.gov/pubmed/30480246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-170051
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