Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13.32 accelerates tumorigenesis

Aberrant chromatin transformation dysregulates gene expression and may be an important driver of tumorigenesis. However, the functional role of chromosomal dynamics in tumorigenesis remains to be elucidated. Here, using in vitro and in vivo experiments, we reveal a novel long noncoding (lncing) driv...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chai, Peiwei, Jia, Ruobing, Jia, Renbing, Pan, Hui, Wang, Shaoyun, Ni, Hongyan, Wang, Huixue, Zhou, Chuandi, Shi, Yingyun, Ge, Shengfang, Zhang, He, Fan, Xianqun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158754/
https://ncbi.nlm.nih.gov/pubmed/29741668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky366
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