Generation of onco-enhancer enhances chromosomal remodeling and accelerates tumorigenesis

Chromatin remodeling impacts the structural neighborhoods and regulates gene expression. However, the role of enhancer-guided chromatin remodeling in the gene regulation remains unclear. Here, using RNA-seq and ChIP-seq, we identified for the first time that neurotensin (NTS) serves as a key oncogen...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chai, Peiwei, Yu, Jie, Jia, Ruobing, Wen, Xuyang, Ding, Tianyi, Zhang, Xiaoyu, Ni, Hongyan, Jia, Renbing, Ge, Shengfang, Zhang, He, Fan, Xianqun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708045/
https://ncbi.nlm.nih.gov/pubmed/33196849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1051
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