Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13.32 accelerates tumorigenesis

Aberrant chromatin transformation dysregulates gene expression and may be an important driver of tumorigenesis. However, the functional role of chromosomal dynamics in tumorigenesis remains to be elucidated. Here, using in vitro and in vivo experiments, we reveal a novel long noncoding (lncing) driv...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Chai, Peiwei, Jia, Ruobing, Jia, Renbing, Pan, Hui, Wang, Shaoyun, Ni, Hongyan, Wang, Huixue, Zhou, Chuandi, Shi, Yingyun, Ge, Shengfang, Zhang, He, Fan, Xianqun
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158754/
https://ncbi.nlm.nih.gov/pubmed/29741668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky366
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