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Chemical genetic inhibition of DEAD-box proteins using covalent complementarity
DEAD-box proteins are an essential class of enzymes involved in all stages of RNA metabolism. The study of DEAD-box proteins is challenging in a native setting since they are structurally similar, often essential and display dosage sensitivity. Pharmacological inhibition would be an ideal tool to pr...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6158709/ https://ncbi.nlm.nih.gov/pubmed/30102385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky706 |
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