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Herpes Simplex Virus 1 γ(1)34.5 Protein Inhibits STING Activation That Restricts Viral Replication
The γ(1)34.5 gene of herpes simplex virus 1 (HSV-1) encodes a virulence factor that promotes viral pathogenesis. Although it perturbs TANK-binding kinase 1 (TBK1) in the complex network of innate immune pathways, the underlying mechanism is obscure. Here we report that HSV-1 γ(1)34.5 targets stimula...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6158424/ https://ncbi.nlm.nih.gov/pubmed/30045990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01015-18 |
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