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A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

Brain function depends on interaction of diverse cell types whose gene expression and identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major epigenetic modifications, methylcytosine (mC) and hydroxymethylcytosine (hmC), yet their cell type–specific landscapes and re...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Kozlenkov, Alexey, Li, Junhao, Apontes, Pasha, Hurd, Yasmin L., Byne, William M., Koonin, Eugene V., Wegner, Michael, Mukamel, Eran A., Dracheva, Stella
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157969/
https://ncbi.nlm.nih.gov/pubmed/30263963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6190
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