A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

Brain function depends on interaction of diverse cell types whose gene expression and identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major epigenetic modifications, methylcytosine (mC) and hydroxymethylcytosine (hmC), yet their cell type–specific landscapes and re...

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Publicado en:Sci Adv
Autores principales: Kozlenkov, Alexey, Li, Junhao, Apontes, Pasha, Hurd, Yasmin L., Byne, William M., Koonin, Eugene V., Wegner, Michael, Mukamel, Eran A., Dracheva, Stella
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157969/
https://ncbi.nlm.nih.gov/pubmed/30263963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6190
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