A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

Brain function depends on interaction of diverse cell types whose gene expression and identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major epigenetic modifications, methylcytosine (mC) and hydroxymethylcytosine (hmC), yet their cell type–specific landscapes and re...

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Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Kozlenkov, Alexey, Li, Junhao, Apontes, Pasha, Hurd, Yasmin L., Byne, William M., Koonin, Eugene V., Wegner, Michael, Mukamel, Eran A., Dracheva, Stella
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157969/
https://ncbi.nlm.nih.gov/pubmed/30263963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6190
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