Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis

Chemokine synergy-inducing molecules are emerging as regulating factors in cell migration. The alarmin HMGB1, in its reduced form, can complex with CXCL12 enhancing its activity on monocytes via the chemokine receptor CXCR4, while the form containing a disulfide bond, by binding to TLR2 or TLR4, ini...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Immunol
Hlavní autoři: Cecchinato, Valentina, D'Agostino, Gianluca, Raeli, Lorenzo, Nerviani, Alessandra, Schiraldi, Milena, Danelon, Gabriela, Manzo, Antonio, Thelen, Marcus, Ciurea, Adrian, Bianchi, Marco E., Rubartelli, Anna, Pitzalis, Costantino, Uguccioni, Mariagrazia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157448/
https://ncbi.nlm.nih.gov/pubmed/30283452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02118
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky