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Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate
Aims: We aim here to demonstrate that radiation (RT) enhances tumor sensitization by only those Mn complexes that are redox active and cycle with ascorbate (Asc), thereby producing H(2)O(2) and utilizing it subsequently in protein S-glutathionylation in a glutathione peroxidase (GPx)-like manner. In...
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| 出版年: | Antioxid Redox Signal |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Mary Ann Liebert, Inc., publishers
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157436/ https://ncbi.nlm.nih.gov/pubmed/29390861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7218 |
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