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Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate

Aims: We aim here to demonstrate that radiation (RT) enhances tumor sensitization by only those Mn complexes that are redox active and cycle with ascorbate (Asc), thereby producing H(2)O(2) and utilizing it subsequently in protein S-glutathionylation in a glutathione peroxidase (GPx)-like manner. In...

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書誌詳細
出版年:Antioxid Redox Signal
主要な著者: Tovmasyan, Artak, Bueno-Janice, Jacqueline C., Jaramillo, Melba C., Sampaio, Romulo S., Reboucas, Julio S., Kyui, Natalia, Benov, Ludmil, Deng, Brian, Huang, Ting-Ting, Tome, Margaret E., Spasojevic, Ivan, Batinic-Haberle, Ines
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc., publishers 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157436/
https://ncbi.nlm.nih.gov/pubmed/29390861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7218
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