Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate

Aims: We aim here to demonstrate that radiation (RT) enhances tumor sensitization by only those Mn complexes that are redox active and cycle with ascorbate (Asc), thereby producing H(2)O(2) and utilizing it subsequently in protein S-glutathionylation in a glutathione peroxidase (GPx)-like manner. In...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antioxid Redox Signal
Prif Awduron: Tovmasyan, Artak, Bueno-Janice, Jacqueline C., Jaramillo, Melba C., Sampaio, Romulo S., Reboucas, Julio S., Kyui, Natalia, Benov, Ludmil, Deng, Brian, Huang, Ting-Ting, Tome, Margaret E., Spasojevic, Ivan, Batinic-Haberle, Ines
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc., publishers 2018
Pynciau:
Forum Original Research Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157436/
https://ncbi.nlm.nih.gov/pubmed/29390861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7218
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