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Imetelstat, a telomerase inhibitor, is capable of depleting myelofibrosis stem and progenitor cells
Clinical trials of imetelstat therapy have indicated that this telomerase inhibitor might have disease-modifying effects in a subset of patients with myelofibrosis (MF). The mechanism by which imetelstat induces such clinical responses has not been clearly elucidated. Using in vitro hematopoietic pr...
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| Publié dans: | Blood Adv |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156882/ https://ncbi.nlm.nih.gov/pubmed/30242099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018022012 |
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