A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells

Recently, interactions between thrombopoietin (TPO) and its receptor, the myeloproliferative leukemia (MPL) virus oncogene, have been shown to play a role in the development and progression of myeloproliferative neoplasms including myelofibrosis (MF). These observations have led to the development o...

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Publicado en:Blood
Autores principales: Wang, Xiaoli, Haylock, David, Hu, Cing Siang, Kowalczyk, Wioleta, Jiang, Tianbo, Qiu, Jiajing, Mosoyan, Goar, He, Wu, Marshall, Netonia, Mascarenhas, John, Tarasova, Anna, Brody, Joshua, Winkler, David, Hoffman, Ronald
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2016
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929928/
https://ncbi.nlm.nih.gov/pubmed/27114459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-674465
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