A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells

Recently, interactions between thrombopoietin (TPO) and its receptor, the myeloproliferative leukemia (MPL) virus oncogene, have been shown to play a role in the development and progression of myeloproliferative neoplasms including myelofibrosis (MF). These observations have led to the development o...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Xiaoli, Haylock, David, Hu, Cing Siang, Kowalczyk, Wioleta, Jiang, Tianbo, Qiu, Jiajing, Mosoyan, Goar, He, Wu, Marshall, Netonia, Mascarenhas, John, Tarasova, Anna, Brody, Joshua, Winkler, David, Hoffman, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929928/
https://ncbi.nlm.nih.gov/pubmed/27114459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-674465
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