A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells

Recently, interactions between thrombopoietin (TPO) and its receptor, the myeloproliferative leukemia (MPL) virus oncogene, have been shown to play a role in the development and progression of myeloproliferative neoplasms including myelofibrosis (MF). These observations have led to the development o...

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Pubblicato in:Blood
Autori principali: Wang, Xiaoli, Haylock, David, Hu, Cing Siang, Kowalczyk, Wioleta, Jiang, Tianbo, Qiu, Jiajing, Mosoyan, Goar, He, Wu, Marshall, Netonia, Mascarenhas, John, Tarasova, Anna, Brody, Joshua, Winkler, David, Hoffman, Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929928/
https://ncbi.nlm.nih.gov/pubmed/27114459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-674465
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