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The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells
BACKGROUND: Mounting evidence from genome-wide studies of cancer shows that chromatin-mediated epigenetic silencing at large cohorts of genes is strongly linked to a poor prognosis. This mechanism is thought to prevent cell differentiation and enable evasion of the immune system. Drugging the cancer...
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| Pubblicato in: | BMC Syst Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156859/ https://ncbi.nlm.nih.gov/pubmed/30253781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0608-4 |
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