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Synthetic Reversal of Epigenetic Silencing

Controlling cell fate-determining gene expression is key to stem cell differentiation, tissue regeneration, and cancer therapy. To date, custom-built transcription factors recognize the information encoded in specific DNA sequences. Chromatin proteins undergo covalent modifications and form complexe...

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Detalhes bibliográficos
Main Authors: Haynes, Karmella A., Silver, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149311/
https://ncbi.nlm.nih.gov/pubmed/21669865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.229567
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