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Synthetic Reversal of Epigenetic Silencing
Controlling cell fate-determining gene expression is key to stem cell differentiation, tissue regeneration, and cancer therapy. To date, custom-built transcription factors recognize the information encoded in specific DNA sequences. Chromatin proteins undergo covalent modifications and form complexe...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149311/ https://ncbi.nlm.nih.gov/pubmed/21669865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.229567 |
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