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Beyond the Four Bases: A Home Run for Synthetic Epigenetic Control?

Park et al. (2019) create a synthetic self-propagating adenine methylation system for epigenetic control in human cells. Targeting adenine allows their modular system to act orthogonally to most epigenetic processes, thereby opening the door for novel methods of controlling gene expression.

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Chang, Timothy Z., Kuo, James, Silver, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561724/
https://ncbi.nlm.nih.gov/pubmed/30951651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.016
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