CCAR‐1 is a negative regulator of the heat‐shock response in Caenorhabditis elegans

Defects in protein quality control during aging are central to many human diseases, and strategies are needed to better understand mechanisms of controlling the quality of the proteome. The heat‐shock response (HSR) is a conserved survival mechanism mediated by the transcription factor HSF1 which fu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Brunquell, Jessica, Raynes, Rachel, Bowers, Philip, Morris, Stephanie, Snyder, Alana, Lugano, Doreen, Deonarine, Andrew, Westerheide, Sandy D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156500/
https://ncbi.nlm.nih.gov/pubmed/30003683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12813
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