CCAR‐1 is a negative regulator of the heat‐shock response in Caenorhabditis elegans

Defects in protein quality control during aging are central to many human diseases, and strategies are needed to better understand mechanisms of controlling the quality of the proteome. The heat‐shock response (HSR) is a conserved survival mechanism mediated by the transcription factor HSF1 which fu...

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Publicat a:Aging Cell
Autors principals: Brunquell, Jessica, Raynes, Rachel, Bowers, Philip, Morris, Stephanie, Snyder, Alana, Lugano, Doreen, Deonarine, Andrew, Westerheide, Sandy D.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156500/
https://ncbi.nlm.nih.gov/pubmed/30003683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12813
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