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The SIRT1 Modulators AROS and DBC1 Regulate HSF1 Activity and the Heat Shock Response
The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regulated by the transcription factor HSF1, which is activated upon heat shock and other stresses to induce the expression of molecular chaperones. SIRT1 has...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548779/ https://ncbi.nlm.nih.gov/pubmed/23349863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054364 |
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