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Heat Shock and Caloric Restriction Have a Synergistic Effect on the Heat Shock Response in a sir2.1-dependent Manner in Caenorhabditis elegans

The heat shock response (HSR) is responsible for maintaining cellular and organismal health through the regulation of proteostasis. Recent data demonstrating that the mammalian HSR is regulated by SIRT1 suggest that this response may be under metabolic control. To test this hypothesis, we have deter...

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Bibliografische gegevens
Hoofdauteurs: Raynes, Rachel, Leckey, Bruce D., Nguyen, Kevin, Westerheide, Sandy D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436562/
https://ncbi.nlm.nih.gov/pubmed/22778258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353714
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