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Heat Shock and Caloric Restriction Have a Synergistic Effect on the Heat Shock Response in a sir2.1-dependent Manner in Caenorhabditis elegans

The heat shock response (HSR) is responsible for maintaining cellular and organismal health through the regulation of proteostasis. Recent data demonstrating that the mammalian HSR is regulated by SIRT1 suggest that this response may be under metabolic control. To test this hypothesis, we have deter...

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Detalhes bibliográficos
Main Authors: Raynes, Rachel, Leckey, Bruce D., Nguyen, Kevin, Westerheide, Sandy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436562/
https://ncbi.nlm.nih.gov/pubmed/22778258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353714
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