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Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer

Cells must continuously respond to stressful insults via the upregulation of cytoprotective pathways. The longevity factor and deacetylase SIRT1 plays a critical role in coordinating this cellular response to stress. SIRT1 activity and levels are regulated by cellular stressors, including metabolic,...

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Detalhes bibliográficos
Main Authors: Raynes, Rachel, Brunquell, Jessica, Westerheide, Sandy D.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764474/
https://ncbi.nlm.nih.gov/pubmed/24020008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913484497
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