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Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long‐lived animals
Disruption of mitochondrial metabolism and loss of mitochondrial DNA (mtDNA) integrity are widely considered as evolutionarily conserved (public) mechanisms of aging (López‐Otín et al., Cell, 153, 2013 and 1194). Human aging is associated with loss in skeletal muscle mass and function (Sarcopenia),...
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| 出版年: | Aging Cell |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156498/ https://ncbi.nlm.nih.gov/pubmed/30043489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12814 |
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