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Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long‐lived animals
Disruption of mitochondrial metabolism and loss of mitochondrial DNA (mtDNA) integrity are widely considered as evolutionarily conserved (public) mechanisms of aging (López‐Otín et al., Cell, 153, 2013 and 1194). Human aging is associated with loss in skeletal muscle mass and function (Sarcopenia),...
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| Publicado en: | Aging Cell |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156498/ https://ncbi.nlm.nih.gov/pubmed/30043489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12814 |
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