Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity

How tumor microenvironmental forces shape plasticity of cancer cell morphology is poorly understood. Here, we conduct automated histology image and spatial statistical analyses in 514 high grade serous ovarian samples to define cancer morphological diversification within the spatial context of the m...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Heindl, Andreas, Khan, Adnan Mujahid, Rodrigues, Daniel Nava, Eason, Katherine, Sadanandam, Anguraj, Orbegoso, Cecilia, Punta, Marco, Sottoriva, Andrea, Lise, Stefano, Banerjee, Susana, Yuan, Yinyin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156340/
https://ncbi.nlm.nih.gov/pubmed/30254278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06130-3
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